The objective of this research is to develop a smart adjustable standing-sitting wheelchair prototype that can be operated with a smartphone. Its distinctive feature is the ability of standing-sitting adjustment and automatic stop when approaching obstacles. This device can be controlled from installed joysticks and Android smartphone control program. Arduino microcontroller is the main processing unit to control drive system operating. A Linear actuator is used for standing-sitting adjustment. An ultrasonic sensor is used to make the smart wheelchair stop automatically when detect obstacles. A wheelchair tested showed that it can move at a speed of approximately 3 kilometers per hour, take 14.30 seconds for standing upright adjustment, release down 13.56 seconds, and average automatic stopping distance is 43 centimeters.